Semax Reconstitution Calculator (mg → units, %)
A 10 mg vial of Semax mixed with 2 mL of bacteriostatic water holds 5,000 mcg/mL, so a 300 mcg dose is 0.06 mL — 6 units on a U-100 insulin syringe. Change the vial, water or dose below, or read the chart for other mixes.
Semax dilution chart: 300 mcg in units
| Vial | + 1 mL water | + 2 mL water | + 3 mL water | Doses per vial |
|---|---|---|---|---|
| 5 mg | 6 U 0.06 mL · 5,000 mcg/mL | 12 U 0.12 mL · 2,500 mcg/mL | 18 U 0.18 mL · 1,667 mcg/mL | 16.7 |
| 10 mg | 3 U 0.03 mL · 10,000 mcg/mL | 6 U 0.06 mL · 5,000 mcg/mL | 9 U 0.09 mL · 3,333 mcg/mL | 33.3 |
1 mL = 100 units on a U-100 syringe. Water volume changes the units per dose, never the number of doses in the vial.
Measuring Semax: the math that matters
Semax is unusual among the compounds on this site because its clinical form is a nasal solution, not an injection, and nasal solutions are labelled by percentage rather than by dose. The Russian products are 0.1% to 1%. Converting between the two is simple: 1% weight per volume is 10 mg per mL, so 0.1% is 1 mg/mL, or 1,000 mcg/mL.
Research vials of lyophilized Semax, sold in sizes such as 5 mg or 10 mg, turn into a much stronger solution when mixed with a small volume. A 10 mg vial with 1 mL of water is 10,000 mcg/mL, which is 1%. The same vial with 2 mL is 0.5%, and reaching 0.1% would take 10 mL. The calculator reports concentration in mcg/mL; divide that figure by 10,000 to get the percentage.
If a vial is drawn with an insulin syringe, the usual units math applies. With a 10 mg vial and 2 mL of water, the 300 mcg example amount is 0.06 mL, or 6 units on a U-100 syringe. With 1 mL it is 3 units, which is hard to measure on a 1 mL syringe marked every 2 units. A 5 mg vial with 2 mL puts it at 12 units.
A nasal dropper or spray does not deliver a fixed volume the way a syringe does. The dose per drop or per spray depends on the device, so the percentage of the solution alone does not tell you how many micrograms each drop contains. The calculator can tell you the concentration; it cannot tell you what a dropper delivers.
Common Semax measuring mistakes
- Assuming a reconstituted research vial is the same strength as a 0.1% nasal product. A 10 mg vial in 1 mL is ten times stronger.
- Confusing percent with mg/mL. 1% is 10 mg/mL, not 1 mg/mL.
- Treating the example amount on this page as a dose. It is a round number for showing the math.
- Mixing a 10 mg vial with 1 mL and trying to measure 3 units by eye.
- Counting drops as if every drop were the same volume across different droppers.